A systematic review and meta-analysis were undertaken to assess the implications of perioperative red blood cell transfusion on postoperative outcomes following elective major abdominal surgery. Publications from January 1, 2000, to June 6, 2020, in the PubMed, Cochrane, and Scopus databases were meticulously evaluated. Although no randomized controlled trials emerged, out of the 39 observational studies identified, 37 were integrated into the meta-analysis.
The analysis unequivocally establishes that perioperative blood transfusions are correlated with elevated risks of negative postoperative outcomes for elective major abdominal surgeries, spanning both the short and long term. This revelation accentuates the imperative of adopting patient blood management measures, with the end goal being optimizing the use of a patient's own blood and diminishing the reliance on transfusions.
Outcomes following perioperative red blood cell transfusion in patients undergoing elective major abdominal surgery: a systematic review and meta-analysis - British Journal of Anaesthesia (bjanaesthesia.org)