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Internal Medicine

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#TriviaTuesday Lets start off with an easy one.


Q1. Prior to modern medicine’s adaptation of the metric system in the 1700s, the apothecaries’ system of weights and measures formed the basis of pharmaceutical preparations. A present-day remnant of this system is X which is still manufactured and prescribed in the doses Y and ¼ Y. These doses were originally derived from the weight of one grain of barleycorn, a unit designated as 1 gr (short for 1 grain) which was equivalent to a weight of approximately 64.8 mg.

 

Name X and Y, which each of us regularly prescribes.


(Ask for a hint).

Mazen Kherallah
N G
D B T
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Answer for Q1: X is Aspirin Y is 81 mg/324 mg. Aspirin was originally dosed as a factor of the weight of a grain of barely corn- 5 gr (5 x 64.8 = 324mg) was the anti-inflammatory dose. Subsequently 1/4 of that dose, 81 mg found its place as primary prevention for cardiovascular events and strokes for high risk patients. Interestingly, on this day (March 6) in 1899 the pharmaceutical company Bayer trademarked aspirin.

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