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Sepsis & Septic Shock

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The 30 mL/kg fluid resuscitation to all patients as per surviving sepsis campaign guidelines has been challenged in a nice article by Paul Marik that you may be interested to look at here:


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024756/#:~:text=Furthermore%2C%20there%20is%20no%20evidence,greatest%20hoaxes%20of%20modern%20medicine.


The conclusion suggested that an individualized, hemodynamically guided and fluid restricted approach to fluid therapy will improve the outcomes of patients with severe sepsis and septic shock.


I think the CLASSIC trial (Restrictive Fluid in Septic Shock) results will be released in June and will shed more light on the topic before any change in the guidelines.

dr saada aladawi
Hadi Al Yousuf
suray Bakkar
Dr-Yasser Alwali
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