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In-depth Understanding of Resistance in Beta-lactam Antibiotics

In-depth Understanding of Resistance in Beta-lactam Antibiotics

SKU: 2023004

The objectives of this presentation are:

  1. Review the different groups of beta-lactam agents including the penicillins, cephalosporins, carbapenems, and monobactams.
  2. Review the different mechanisms of beta-lactam resistance in gram-negative and gram-positive bacteria.
  3. Present the Ambler classification of beta-lactamases and review the substrate spectrum of each enzyme. We will describe in detail the penicillinases, the broad spectrum beta-lactamases, the extended-spectrum beta-lactmases, the AmpC beta-lactamases, the OXA beta lactamases, and finally the metallo beta-lactamses.
  4. Review the available beta-lactamase inhibitors including the newer agents such as avibactam, rebelbactam, and vaborbactam.
  5. Identify optimal antibiotic regimens for common infectious agents in the ICU setting, more specifically, Carbapenem-resistant Enterobacteriaceae (CRE), multi-drug resistant pseudomonas, and MDR Acinetobacter.



  1. PowerPoint presentation
  2. 46 slides
  3. Size: 7.608 KB
  4. Loyalty free (you can use for any educational pupose).


  • Disclaimer

    The set price of this presentation is not reflective of its value. It is intended to provide a donation that will contribute to ICU REACH fulfilling its objectives and mission.

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