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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Restrictive vs. Liberal Transfusion in Myocardial Infarction: Implications for Clinical Practice
Restrictive vs. Liberal Transfusion in Myocardial Infarction: Implications for Clinical Practice
Mazen Kherallah
Mar 62 min read
Unlocking the Potential of EHR-Based Sepsis Alerts: Insights from the SCREEN Trial
The SCREEN trial provides a significant step forward, but its results should serve as a catalyst for further investigation.
Mazen Kherallah
Dec 12, 20243 min read
Mechanical Thrombectomy in Pulmonary Embolism: Insights from the PEERLESS Trial
The PEERLESS trial provides compelling evidence that LBMT offers an effective and safe alternative to CDT for intermediate-risk PE patients.
Mazen Kherallah
Nov 12, 20244 min read
Time vs Volume Capnography
Volume capnography represents CO₂ concentration against expired volume allowing to account for dead space and CO2 production.
Mazen Kherallah
Nov 12, 20246 min read
Understanding the VExUS Score: A Case Example of Grade 3 Congestion
Grade 3 VExUS score indicating severe venous congestion.
Mazen Kherallah
Nov 4, 20243 min read
Strategies for Successful Weaning from Mechanical Ventilation: What the Latest Research Reveals?
Burns et al. highlight that once-daily screening with pressure-supported SBTs may optimize ICU weaning, guiding personalized critical care.
Mazen Kherallah
Oct 26, 20243 min read
Liberal vs. Restrictive Transfusion Strategies in TBI: A New Perspective!
Based on the TRAIN and HEMOTION trials, liberal transfusion thresholds should be advocated for neurocritically ill patients.
Mazen Kherallah
Oct 23, 20242 min read
SGLT2 Inhibitors Likely Reduce the Incidence of Ventricular Arrhythmias in Heart Failure!
the current evidence supports the integration of SGLT2 inhibitors into treatment protocols for patients with heart failure.
Mazen Kherallah
Sep 30, 20243 min read
One- or two-week Patient-intensivist Continuity of Care in the ICU?
Current evidence does not strongly support extending intensivist continuity from one to two weeks for ICU patients in terms of outcomes
Mazen Kherallah
Aug 18, 20243 min read
The Impact of Intensive Glucose Control in Critically Ill Patients: Insights from a Comprehensive Meta-Analysis
intensive glucose control does not improve survival in critically ill adults and may even pose significant risks of hypoglycemia.
Mazen Kherallah
Aug 14, 20243 min read
The Impact of In-Hospital Violence on Critical Care Practitioners: A Growing Crisis!
In-hospital violence is a growing concern for healthcare facilities, impacting the physical and mental well-being of physicians
Mazen Kherallah
Aug 1, 20243 min read
Tenecteplase in Extended Window: A Promising Alternative for Acute Stroke Treatment!
Tenecteplase is an alternative option in in patients with acute stroke without immediate access to thrombectomy.
Mazen Kherallah
Jul 24, 20243 min read
New Oral Agent for Hereditary Angioedema Treatment: Sebetralstat
Oral sebetralstat represents a leap forward in the management of hereditary angioedema, providing patients with a more accessible and effect
Mazen Kherallah
Jul 8, 20243 min read
Ventricular-Arterial Coupling (Ea/Ees Ratio)
Ventricular-arterial coupling is a dynamic interplay between ventricular contractility and arterial load.
Mazen Kherallah
Jun 29, 20242 min read
Does Achieving Better β-lactam Pharmacokinetic Targets Translate to Better Clinical Outcomes in Septic Patients?
Continuous infusion of β-lactam antibiotics holds promise for better outcomes in sepsis treatment.
Mazen Kherallah
Jun 19, 20243 min read
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation
PPIs can reduce gastrointestinal bleeding and possibly mortality in less severely ill patients, they do not significantly impact mortality.
Mazen Kherallah
Jun 16, 20242 min read
Post-Spontaneous Breathing Trial Reconnection to Mechanical Ventilation for Alveolar Recruitment Recovery
These findings highlight the importance of post-SBT reconnection in recovering alveolar derecruitment after SBT.
Mazen Kherallah
Jun 9, 20242 min read
Understanding Preload of the Left Ventricle: A Key Concept in Cardiovascular Physiology
Preload is a fundamental concept in cardiovascular physiology, essential for understanding the mechanics of the heart. It refers to the...
Mazen Kherallah
May 29, 20243 min read
Hemodynamic Profile in Sepsis and Septic Shock Associated with Vasoplegia: A Pressure-Volume Diagram Perspective
Sepsis is a life-threatening condition characterized by an overwhelming immune response to infection, leading to widespread inflammation...
Mazen Kherallah
May 26, 20243 min read
AI in Critical Care Medicine
AI's integration into critical care medicine offers substantial benefits but also presents challenges that need to be addressed.
Mazen Kherallah
May 22, 20243 min read
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