General Critical Care

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Among the following IV solutions — D5 ½ NS, Albumin, Normal Saline (NS), and Lactated Ringer (LR) — the one with the highest osmolality is D5 ½ NS.

🔎 Here’s why:

• Osmolality reflects the number of dissolved particles in a solution.

• For electrolytes (Na⁺, K⁺, Cl⁻, lactate), mEq/L ≈ mOsm/L.

Therefore:

• Normal Saline (0.9% NaCl): 154 Na⁺ + 154 Cl⁻ = 308 mOsm/L