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Internal Medicine

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This population-based cohort study in Denmark, examining individuals born between 1977-2018 and followed up to 40 years, found tooth agenesis associated with increased risks of several cancers before 40 years, notably neuroblastoma, nephroblastoma, hepatoblastoma, osteosarcoma, colorectal carcinomas, and bladder carcinomas, with HRs ranging from 2.19 to 7.10. The study highlights the need for further research on the clinical implications of these findings.

Congenital Tooth Agenesis and Risk of Early-Onset Cancer | Oncology | JAMA Network Open | JAMA Network

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