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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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The PILOT Trial and Evolution of Evidence for Oxygen Targets in the Critically Ill Patients
It appears that there is no significant difference in mortality or other outcomes when critically ill patients are given a conservative oxyg

Mazen Kherallah
Oct 27, 20225 min read


Selection of Paralytic and Induction Agents in RSI
Selection of a paralytic and induction agents in rapid sequence intubation (RSI).

Mazen Kherallah
Oct 25, 20227 min read


Evolution on Evidence for ECCO2R Use in ARDS Patients
Even though extracorporeal CO2 removal might appear appealing because it helps reduce the mechanical force of ventilation, evidence showed

Mazen Kherallah
Oct 18, 20223 min read


Echocardiographic Signs of Right Ventricular Strain in Acute Pulmonary Embolism
Right ventricular (RV) strain, as seen on echocardiography, is a common finding in patients with pulmonary embolism (PE). This is due to...

Mazen Kherallah
Oct 14, 20225 min read


High Peak Inspiratory Pressure Troubleshooting
Patients on the volume control mode of ventilation may have an increased peak pressure that could be due to increased airway resistance,

Mazen Kherallah
Oct 9, 20225 min read


P 0.1 Predicts Respiratory Drive in Patients on Mechanical Ventilation
The respiratory drive is the intensity of the neural stimulus that determines how much the respiratory muscles contract

Mazen Kherallah
Oct 8, 20224 min read


Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis
aggressive fluid resuscitation in the treatment of acute pancreatitis was found to be linked with a higher risk of volume overload

Mazen Kherallah
Oct 4, 20223 min read


Strategies to Implement Early Mobility Programs Successfully in the ICU
In conclusion, the barriers to early mobilization in the ICU are many and varied. This barriers could be related to patient status, organiza

Mazen Kherallah
Oct 3, 20223 min read


End-expiratory Occlusion test and the assessment of transpulmonary pressure
EEO test is the pressure generated by the inspiratory effort of the patient against occluded airway.

Mazen Kherallah
Sep 27, 20223 min read


How End-expiratory Occlusion test (EEO) Test Can Help Assess Fluid Responsiveness in ICU Patients!
The End-Expiratory Occlusion Test is a reliable tool used by clinicians to assess fluid responsiveness in ICU patients. The test can be used

Mazen Kherallah
Sep 23, 20225 min read


Burnout Syndrome among ICU Healthcare Professionals
Critical care health professionals are at high risk for burnout syndrome. This debilitating condition can cause physical and emotional...

Mazen Kherallah
Sep 23, 20225 min read


Ultrasound Assessment of Spontaneous Effort on Mechanical Ventilation
Us if ultrasound of the diaphragm to identify spontaneous inspiratory efforts and facilitate protection of lungs and diaphragm

Mazen Kherallah
Sep 18, 20224 min read


Should We Use a Higher Blood-Pressure Target in Comatose Survivors of Cardiac Arrest?
Higher mean arterial pressure in patients after cardiac arrest does not improve outcome

Mazen Kherallah
Sep 6, 20223 min read


Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19
Sabizabulin reduced 60-day all-cause mortality in hospitalized patients with moderate to severe COVID-19 infection

Mazen Kherallah
Aug 1, 20223 min read


Hypothermic versus Normothermic Temperature Control after Cardiac Arrest
Hypothermia at 33°C does not reduce 6-month mortality and does not improve 6-month neurological outcome compared to normothermia.

Mazen Kherallah
Jul 4, 20223 min read


Diastolic Shock Index: What it Means and how is it Interpreted?
it seems appropriate to monitor DSI in septic patients due to its prognostic value and ability to guide early administration of vasopressors

Mazen Kherallah
Jul 3, 20223 min read


Vasopressors in Septic Shock: Timing, Choice & Target
A practical review of vasopressor therapy in septic shock—when to start, which agent to choose, and what mean arterial pressure to target—drawing on SEPSISPAM and other key trials behind the 65–70 mmHg goal.

Mazen Kherallah
Jun 8, 20224 min read


Short vs. Long Antibiotic Course for Ventilator-associated Pneumonia (VAP) and Pseudomonas VAP
Ventilator-associated pneumonia is the most common infection among the critically ill patients as it accounts for about 25% of infections

Mazen Kherallah
May 22, 20225 min read


Evolution of Evidence for use of HES in Sepsis & Septic Shock
Fluid resuscitation with HES 130/0.42 in patients with severe sepsis is associated with an increased risk of death at day 90.

Mazen Kherallah
May 5, 20223 min read


Approach to Vasopressor Support in Septic Shock
Approach to Vasopressor Support in Septic Shock

Mazen Kherallah
Apr 23, 20226 min read
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