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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Omicron "A Variant of Concern"
The CDC defines the "Variant of Concern" (VOC) for an new variant for which there is evidence of an increase in transmissibility, more...

Mazen Kherallah
Dec 6, 20211 min read


Pathophysiology-based Understanding of Respiratory Failure
The respiratory failure is an imbalance between the load (resistive, elastic, or metabolic) and the neuromuscular competence

Mazen Kherallah
Nov 24, 20212 min read


Stepwise Approach in the Management of ARDS*
Various interventions visually and the following text explains the evidence supporting these interventions.

Mazen Kherallah
Nov 20, 20214 min read


Management of Status Epilepticus
A stepwise approach to the management of status epilepticus in adults of more than 40 Kg of weight based on the most recent evidence.

Mazen Kherallah
Nov 11, 20211 min read


Anticoagulation in Continuous Renal Replacement Therapy
Dialysis fiber clotting can be a major issue encountered during prolonged sessions of continuous renal replacement therapy (CRRT) in the...

Mazen Kherallah
Nov 8, 20211 min read


Low vs Higher Dose Dexamethasone for COVID-19 Patients
In this trial, the adjusted point estimate for 28-day mortality was 4.5 percentage points lower in the 12 mg of dexamethasone group than...

Mazen Kherallah
Oct 26, 20211 min read


Clipping or Coiling for Ruptured Cerebral Aneurysms!
The goal of both surgery (clipping) and endovascular (coiling) treatment is to exclude the lumen of the aneurysm from circulation while pres

Mazen Kherallah
Oct 24, 20211 min read


Progression of EEG in Metabolic Encephalopathy
Normal EEG waves: Beta (14-30 Hz), Alpha: 8-13, Theta (4-7 Hz), Delta (<3.5 Hz): The earliest signs of metabolic encephalopathy is a mild...

Mazen Kherallah
Sep 19, 20211 min read


Anticoagulation in COVID-19
It seems that selected group of patients may benefit of full anticoagulation but has to start early enough before organ damage occurs.

Mazen Kherallah
Sep 3, 20213 min read


Decompressive Craniectomy and a Stepwise Approach to Elevated ICP in Patients with Severe TBI
Elevated intracranial pressure (ICP) is associated with increased mortality and worse outcome in patients with traumatic brain injury...

Mazen Kherallah
Aug 28, 20212 min read


"Time is Brain": Management of Acute Ischemic Stroke!
The sooner brain reperfusion therapy is initiated after an acute ischemic stroke (AIS), the greater the likelihood of a better outcome....

Mazen Kherallah
Aug 26, 20214 min read


The Story of Targeted Temperature Management after Cardiac Arrest!
In the past two decades, the critical care field has witnessed the development of new concepts and interventions aiming at improving...

Mazen Kherallah
Aug 23, 20214 min read


Awake Prone Position Reduces Need of Mechanical Ventilation in COVID-19 Respiratory Failure !
Awake prone position has been widely used in COVID-19 patients with respiratory failure and incorporated in clinical guidelines and...

Mazen Kherallah
Aug 22, 20212 min read


Full Anticoagulation in Critically Ill COVID-19 Patients
In critically ill patients with Covid-19, an initial strategy of therapeutic-dose anticoagulation with unfractionated or...

Mazen Kherallah
Aug 9, 20211 min read


Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock
192 patients were admitted to the cardiac ICU with cardiogenic shock and were randomized to receive either milrinone or dobutamine. The...

Mazen Kherallah
Aug 9, 20211 min read


The Anti-vaccine Con Job Is Becoming Untenable
https://www.theatlantic.com/ideas/archive/2021/08/vaccine-refusers-dont-want-blue-americas-respect/619627/

Nabil Abouchala
Aug 5, 20211 min read


A blood marker predicts who gets ‘breakthrough’ COVID
High levels of virus-blocking antibodies confer protection to vaccinated people as they are less likely to get infected when exposed to...

Nabil Abouchala
Aug 4, 20211 min read


MRI Brain FLAIR, DWI, and SWI
Fluid Attenuated Inversion Recovery (Flair) and diffusion-weighted imaging

Mazen Kherallah
Aug 2, 20212 min read


MRI Images T1, T2, and FLAIR
luid Attenuated Inversion Recovery (Flair) is similar to a T2-weighted image except that the TE and TR times are very long.

Mazen Kherallah
Jul 31, 20211 min read


Ethical Dilemma!
A 65-year-old man who was diagnosed with amyotrophic lateral sclerosis three years ago presented to the emergency department for...

Mazen Kherallah
Jul 28, 20211 min read
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