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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Blood Pressure Management After Successful Thrombectomy
We follow the American Heart Association and the European Stroke Organization guidelines and maintain systolic blood pressure <180 mm Hg
Mazen Kherallah
Sep 22, 20234 min read
The Use of Mechanical Circulatory Support Devices in Acute Myocardial Infarction & Cardiogenic Shock
None of the temporary MCS devices demonstrated a significant reduction in mortality when compared to initial medical therapy
Mazen Kherallah
Aug 29, 20232 min read
Awareness With Paralysis (AWP) During Intubation in the ICU
Awareness with paralysis is more frequent in the ICU than in the operating room, potentially reaching 12%.
Mazen Kherallah
Aug 20, 20235 min read
Cracking the Code: Controversies in ACLS Pharmacotherapy
In this post we discuss the literature surrounding pharmacotherapy interventions that can be utilized during advanced cardiac life support.
Sam markle
Aug 15, 202311 min read
Intermittent versus extended infusion of beta-lactams in sepsis!
Beta-lactams are a category of antibiotics that are most effective when their plasma concentrations persistently exceed the minimum...
Mazen Kherallah
Jul 17, 20235 min read
4-Factor Prothrombin Complex Concentrate in Trauma Patients: The PROCOAG Trial!
The trial did not find any beneficial effects of adding 4F-PCC to a ratio-based transfusion strategy in patients with severe trauma at risk
Mazen Kherallah
Jul 13, 20234 min read
Challenging the Practice of "30 mL per Kg bolus" in all patients with sepsis and septic shock!
Fluid resuscitation in septic shock requires individualized assessment. Evidence-based initial bolus, followed by restrictive strategy.
Mazen Kherallah
Jul 10, 20239 min read
Evidence Summary for Haloperidol Use in the Prevention & Treatment of Delirium in the ICU!
Current evidence does not support the routine use of antipsychotic medications for the treatment or prevention of delirium in critically ill
Mazen Kherallah
Jun 26, 20234 min read
How Fast Should a Fluid Bolus be Given?
Rapid fluid infusion rates could potentially enhance stroke volume and cardiac output but has unknown effect on patient-centered ou
Mazen Kherallah
Jun 16, 20233 min read
Should we Consider Nicotine Replacement Therapy (NRT) for Our Smoker Critically Ill Patients?
This review highlights the lack of strong evidence supporting its use, despite suggested benefits for withdrawal symptoms.
Namareq Aldardeer
Jun 10, 20236 min read
Have You Ever Considered Diuretics in Managing Intermediate-Risk Acute Pulmonary Embolism?
PE patients: RVD, not overload, is the concern. Diuretics are complex; they may relieve RV pressure but worsen stability.
Mazen Kherallah
Jun 8, 20233 min read
Evidence Summary for VTE Prophylaxis in Critically Ill Patients!
LMW heparin reduced DVT incidence significantly compared to control treatments, and it appears to be more effective than UFH.
Mazen Kherallah
Jun 2, 20237 min read
Evolution of Evidence for Steroids in Septic Shock!
Septic shock management remains challenging. Steroid use has inconsistent findings on mortality. Hydrocortisone with/without fludrocortisone
Mazen Kherallah
May 30, 20234 min read
Proposed Approach to Prophylactic Platelet Transfusions Prior to CVC Placement
Bleeding Risk in Primary and Subgroup Analyses.
Mazen Kherallah
May 30, 20233 min read
Should We Change the Defibrillation Strategies in Out-of-Hospital Cardiac Arrest?
New defibrillation techniques, DSED and VC, show higher survival rates and improved neurologic outcomes for refractory ventricular fibrillat
Mazen Kherallah
May 29, 20233 min read
First-Ever RSV Vaccine: Arexvy Breaks Ground with FDA Approval
Respiratory syncytial virus (RSV) infection is a common cause of respiratory illnesses in the lower respiratory tract worldwide. It poses...
Mazen Kherallah
May 24, 20235 min read
Shivering Management During Targeted Temperature Management
The benefits of a multimodal approach in managing shivering during normothermia-targeted temperature management (TTM).
Jennifer Spadgenske
May 12, 20234 min read
Controversies Surrounding Targeted Temperature Management (TTM) in Cardiac Arrest
Hypothermia (≤36°C) reduces lactate accumulation and excitatory neurotransmitter release, but TTM-2 found 32°C TTM increased arrhythmias. TT
Jennifer Spadgenske
May 8, 20235 min read
Phenylephrine in Patients with Septic Shock
Phenylephrin
Phenylephrine causes vasoconstriction, increasing blood pressure, but may lead to adverse effects. Further research is needed.
Namareq Aldardeer
May 7, 20238 min read
Blood Pressure Targets in Acute Stroke
Blood pressure management plays a crucial role in the treatment of acute intracerebral hemorrhage (ICH) and ischemic stroke. While...
Mazen Kherallah
May 6, 20237 min read
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