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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Hypothermia vs Normothermia in Patients With Cardiac Arrest and Nonshockable Rhythm
Evidence supports using normothermia in patients with coma after cardiac arrest with nonshockable rhythm compared to hypothermia.
Mazen Kherallah
Dec 28, 20235 min read
Cefepime or Piperacillin/tazobactam Empirically for Gram-negative Infections in the Hospital settings
This trial suggests comparable risks of acute kidney injury and death between cefepime and piperacillin/tazobactam.
Mazen Kherallah
Dec 23, 20233 min read
Doing Less is Actually Doing More: The NICO Trial!
In cases of coma due to acute poisoning, a conservative airway management strategy could be more beneficial than routine intubation.
Mazen Kherallah
Dec 6, 20232 min read
Restrictive vs Liberal Transfusion Strategy in Patients with Myocardial Infarction and Anemia
A liberal transfusion strategy did not significantly reduce the risk of recurrent myocardial infarction or death at 30 days in MI and anemia
Mazen Kherallah
Nov 15, 20234 min read
β-blockers and Sepsis (The STRESS-L Trial)
β-blockers do not improve outcomes in septic shock and maybe harmful
Mazen Kherallah
Nov 11, 20232 min read
Bayesian Analysis Simplified!
Bayesian analysis integrates prior knowledge with current evidence to come closer to the truth.
Mazen Kherallah
Nov 6, 20233 min read
Would you Consider Using Inhaled Amikacin to Prevent from VAP?
Inhaled amikacin could be a viable option for preventing VAP in patients who are on mechanical ventilation for longer than 72 hours.
Mazen Kherallah
Oct 31, 20233 min read
Diminishing Utilization of Prone Positioning for Severe ARDS Patients After COVID-19
The findings underscore a concerning downtrend in the use of prone positioning for managing severe ARDS in COVID-19 patients.
Mazen Kherallah
Oct 13, 20232 min read
Should early lumbar cerebrospinal fluid drain be considered for aneurysmal subarachnoid hemorrhage?
Early lumbar cerebrospinal fluid drainage should be considered for patients following an aneurysmal subarachnoid hemorrhage.
Mazen Kherallah
Sep 29, 20233 min read
Ultrasound-Guided CVC: Biplane vs. Single-Plane Approaches
Biplane ultrasound-guided method is notably superior to the single-plane technique.
Mazen Kherallah
Sep 27, 20232 min read
Blood Pressure Management After Successful Thrombectomy
We follow the American Heart Association and the European Stroke Organization guidelines and maintain systolic blood pressure <180 mm Hg
Mazen Kherallah
Sep 22, 20234 min read
The Use of Mechanical Circulatory Support Devices in Acute Myocardial Infarction & Cardiogenic Shock
None of the temporary MCS devices demonstrated a significant reduction in mortality when compared to initial medical therapy
Mazen Kherallah
Aug 29, 20232 min read
Awareness With Paralysis (AWP) During Intubation in the ICU
Awareness with paralysis is more frequent in the ICU than in the operating room, potentially reaching 12%.
Mazen Kherallah
Aug 20, 20235 min read
Cracking the Code: Controversies in ACLS Pharmacotherapy
In this post we discuss the literature surrounding pharmacotherapy interventions that can be utilized during advanced cardiac life support.
Sam markle
Aug 15, 202311 min read
Intermittent versus extended infusion of beta-lactams in sepsis!
Beta-lactams are a category of antibiotics that are most effective when their plasma concentrations persistently exceed the minimum...
Mazen Kherallah
Jul 17, 20235 min read
4-Factor Prothrombin Complex Concentrate in Trauma Patients: The PROCOAG Trial!
The trial did not find any beneficial effects of adding 4F-PCC to a ratio-based transfusion strategy in patients with severe trauma at risk
Mazen Kherallah
Jul 13, 20234 min read
Challenging the Practice of "30 mL per Kg bolus" in all patients with sepsis and septic shock!
Fluid resuscitation in septic shock requires individualized assessment. Evidence-based initial bolus, followed by restrictive strategy.
Mazen Kherallah
Jul 10, 20239 min read
Evidence Summary for Haloperidol Use in the Prevention & Treatment of Delirium in the ICU!
Current evidence does not support the routine use of antipsychotic medications for the treatment or prevention of delirium in critically ill
Mazen Kherallah
Jun 26, 20234 min read
How Fast Should a Fluid Bolus be Given?
Rapid fluid infusion rates could potentially enhance stroke volume and cardiac output but has unknown effect on patient-centered ou
Mazen Kherallah
Jun 16, 20233 min read
Should we Consider Nicotine Replacement Therapy (NRT) for Our Smoker Critically Ill Patients?
This review highlights the lack of strong evidence supporting its use, despite suggested benefits for withdrawal symptoms.
Namareq Aldardeer
Jun 10, 20236 min read
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