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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Evolution of Evidence for Steroids in Septic Shock!
Septic shock management remains challenging. Steroid use has inconsistent findings on mortality. Hydrocortisone with/without fludrocortisone
Mazen Kherallah
May 30, 20234 min read
Proposed Approach to Prophylactic Platelet Transfusions Prior to CVC Placement
Bleeding Risk in Primary and Subgroup Analyses.
Mazen Kherallah
May 30, 20233 min read
Should We Change the Defibrillation Strategies in Out-of-Hospital Cardiac Arrest?
New defibrillation techniques, DSED and VC, show higher survival rates and improved neurologic outcomes for refractory ventricular fibrillat
Mazen Kherallah
May 29, 20233 min read
First-Ever RSV Vaccine: Arexvy Breaks Ground with FDA Approval
Respiratory syncytial virus (RSV) infection is a common cause of respiratory illnesses in the lower respiratory tract worldwide. It poses...
Mazen Kherallah
May 24, 20235 min read
Shivering Management During Targeted Temperature Management
The benefits of a multimodal approach in managing shivering during normothermia-targeted temperature management (TTM).
Jennifer Spadgenske
May 12, 20234 min read
Controversies Surrounding Targeted Temperature Management (TTM) in Cardiac Arrest
Hypothermia (≤36°C) reduces lactate accumulation and excitatory neurotransmitter release, but TTM-2 found 32°C TTM increased arrhythmias. TT
Jennifer Spadgenske
May 8, 20235 min read
Phenylephrine in Patients with Septic Shock
Phenylephrin
Phenylephrine causes vasoconstriction, increasing blood pressure, but may lead to adverse effects. Further research is needed.
Namareq Aldardeer
May 7, 20238 min read
Blood Pressure Targets in Acute Stroke
Blood pressure management plays a crucial role in the treatment of acute intracerebral hemorrhage (ICH) and ischemic stroke. While...
Mazen Kherallah
May 6, 20237 min read
The Terrifying Scenario of Cannot Intubate and Cannot Oxygenate!
This blog post shares a real-life, heart-pounding experience of managing a "cannot intubate, cannot oxygenate" situation in the ICU.
Mazen Kherallah
May 1, 20237 min read
Understanding Thromboelastography (TEG)
Thromboelastography (TEG) evaluates blood clotting ability and identifies abnormalities in the coagulation system.
Mazen Kherallah
Apr 30, 20232 min read
Rethinking Enteral Feeding Practices Prior to Extubation: Insights from a Recent Study!
Evaluation of enteral feeding practices prior to extubation in mechanically ventilated patients in the intensive care units.
Mazen Kherallah
Apr 28, 20233 min read
Thromboelastography (TEG) is a Better Indicator of Hemostasis in Cirrhotic Patients
Thromboelastography (TEG)-guided transfusion reduces blood component use without increasing bleeding complications.
Mazen Kherallah
Apr 26, 20235 min read
How long should antibiotics be given for VAP caused by non-fermenting gram-negative bacteria?
Discussion of duration of antibiotic course for Non-Fermenting Gram-Negative Bacteria causing ventilator-associated pneumonia (VAP)
Mazen Kherallah
Apr 19, 20234 min read
Potential Therapeutic Targets for Sepsis: Gasotransmitters (i.e. Hydroxocobalamin)
NO and H2S are important mediators of sepsis pathophysiology. Modulating their levels may offer novel therapeutic opportunities in Sepsis.
Mazen Kherallah
Apr 15, 20233 min read
The Use of Midodrine for Persistent Vasoplegia and Inability to Wean IV Vasopressors?
The evidence on midodrine for persistent vasoplegia after septic shock is mixed, with the largest trial not supporting its routine use.
Mazen Kherallah
Apr 12, 20235 min read
Endovascular Thrombectomy for Patients with Large Ischemic Strokes: A Review of Recent Evidence!
Endovascular thrombectomy for patients with large ischemic strokes is associated with improved functional outcomes.
Mazen Kherallah
Apr 10, 20236 min read
Tranexamic Acid in the Management of Hemoptysis!
Inroduction Hemoptysis is a common and potentially life-threatening condition that requires prompt diagnosis and management. Tranexamic...
Mazen Kherallah
Apr 9, 20234 min read
Methylene blue as a vasopressor adjunct in septic shock: a promising therapy?
Septic shock is a life-threatening condition that occurs when an infection triggers a systemic inflammatory response that leads to organ...
Mazen Kherallah
Apr 8, 20235 min read
What is the Optimal Sequence of Discontinuation for vasopressors in Septic Shock?
Septic shock is a life-threatening condition that requires timely and effective treatment to improve patient outcomes. Vasopressors,...
Mazen Kherallah
Apr 6, 20233 min read
What is the Optimal Timing for Vasopressin in Patients with Septic Shock?
If the targeted perfusion objectives are not achieved using moderate dosages of the primary vasopressor, determining whether to introduce...
Mazen Kherallah
Apr 5, 20235 min read
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