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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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The Terrifying Scenario of Cannot Intubate and Cannot Oxygenate!
This blog post shares a real-life, heart-pounding experience of managing a "cannot intubate, cannot oxygenate" situation in the ICU.
Mazen Kherallah
May 1, 20237 min read
Understanding Thromboelastography (TEG)
Thromboelastography (TEG) evaluates blood clotting ability and identifies abnormalities in the coagulation system.
Mazen Kherallah
Apr 30, 20232 min read
Rethinking Enteral Feeding Practices Prior to Extubation: Insights from a Recent Study!
Evaluation of enteral feeding practices prior to extubation in mechanically ventilated patients in the intensive care units.
Mazen Kherallah
Apr 28, 20233 min read
Thromboelastography (TEG) is a Better Indicator of Hemostasis in Cirrhotic Patients
Thromboelastography (TEG)-guided transfusion reduces blood component use without increasing bleeding complications.
Mazen Kherallah
Apr 26, 20235 min read
How long should antibiotics be given for VAP caused by non-fermenting gram-negative bacteria?
Discussion of duration of antibiotic course for Non-Fermenting Gram-Negative Bacteria causing ventilator-associated pneumonia (VAP)
Mazen Kherallah
Apr 19, 20234 min read
Potential Therapeutic Targets for Sepsis: Gasotransmitters (i.e. Hydroxocobalamin)
NO and H2S are important mediators of sepsis pathophysiology. Modulating their levels may offer novel therapeutic opportunities in Sepsis.
Mazen Kherallah
Apr 15, 20233 min read
The Use of Midodrine for Persistent Vasoplegia and Inability to Wean IV Vasopressors?
The evidence on midodrine for persistent vasoplegia after septic shock is mixed, with the largest trial not supporting its routine use.
Mazen Kherallah
Apr 12, 20235 min read
Endovascular Thrombectomy for Patients with Large Ischemic Strokes: A Review of Recent Evidence!
Endovascular thrombectomy for patients with large ischemic strokes is associated with improved functional outcomes.
Mazen Kherallah
Apr 10, 20236 min read
Tranexamic Acid in the Management of Hemoptysis!
Inroduction Hemoptysis is a common and potentially life-threatening condition that requires prompt diagnosis and management. Tranexamic...
Mazen Kherallah
Apr 9, 20234 min read
Methylene blue as a vasopressor adjunct in septic shock: a promising therapy?
Septic shock is a life-threatening condition that occurs when an infection triggers a systemic inflammatory response that leads to organ...
Mazen Kherallah
Apr 8, 20235 min read
What is the Optimal Sequence of Discontinuation for vasopressors in Septic Shock?
Septic shock is a life-threatening condition that requires timely and effective treatment to improve patient outcomes. Vasopressors,...
Mazen Kherallah
Apr 6, 20233 min read
What is the Optimal Timing for Vasopressin in Patients with Septic Shock?
If the targeted perfusion objectives are not achieved using moderate dosages of the primary vasopressor, determining whether to introduce...
Mazen Kherallah
Apr 5, 20235 min read
When Should a Central Venous Catheter Be Placed for Vasopressor Infusion?
Historically, there has been concern regarding the administration of vasopressors through peripheral venous catheters (PVCs) due to the...
Mazen Kherallah
Apr 1, 20233 min read
Should We Adopt Extended Proning Position for COVID-19 ARDS Patients?
Prone positioning ventilation (PPV) has been a valuable rescue therapy for patients with severe hypoxemia and ARDS, offering benefits in...
Mazen Kherallah
Mar 31, 20233 min read
Should More Lenient Guidelines be Considered for the Treatment Hyponatremia?
Hyponatremia, a common electrolyte imbalance in hospitalized patients, can independently predict mortality and is linked to longer...
Mazen Kherallah
Mar 30, 20233 min read
6 Compartment Models for Regional Ventilation-perfusion Matching in ARDS
The distribution of V/Q compartments in ARDS is not uniform, and it differs from one patient to another.
Mazen Kherallah
Mar 29, 20232 min read
Should we add fludrocortisone to patients with septic shock who are treated with hydrocortisone?
Although previous clinical trials have shown reduced mortality with combined hydrocortisone-fludrocortisone, guidelines recommend...
Mazen Kherallah
Mar 28, 20232 min read
The Wonder Drug Again: Early Hydrocortisone Treatment Saves Lives from Severe Pneumonia!
The potential of glucocorticoids to reduce mortality in patients with severe community-acquired pneumonia through their anti-inflammatory...
Mazen Kherallah
Mar 25, 20234 min read
Turning the Tide: Can Active Fluid De-resuscitation Enhance Outcomes in Septic Shock Patients?
De-resuscitation in septic shock refers to the process of actively removing excess fluids from a patient after their condition is stabalized
Mazen Kherallah
Mar 15, 20233 min read
Colistin: A Useful Past, But Time to Move Beyond
The OVERCOME trial (Colistin Monotherapy Versus Combination Therapy for Carbapenem-Resistant Organisms), published in NEJM Evidence, is...
Mazen Kherallah
Mar 14, 20233 min read
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