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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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When Should a Central Venous Catheter Be Placed for Vasopressor Infusion?
Historically, there has been concern regarding the administration of vasopressors through peripheral venous catheters (PVCs) due to the...
Mazen Kherallah
Apr 1, 20233 min read
Should We Adopt Extended Proning Position for COVID-19 ARDS Patients?
Prone positioning ventilation (PPV) has been a valuable rescue therapy for patients with severe hypoxemia and ARDS, offering benefits in...
Mazen Kherallah
Mar 31, 20233 min read
Should More Lenient Guidelines be Considered for the Treatment Hyponatremia?
Hyponatremia, a common electrolyte imbalance in hospitalized patients, can independently predict mortality and is linked to longer...
Mazen Kherallah
Mar 30, 20233 min read
6 Compartment Models for Regional Ventilation-perfusion Matching in ARDS
The distribution of V/Q compartments in ARDS is not uniform, and it differs from one patient to another.
Mazen Kherallah
Mar 29, 20232 min read
Should we add fludrocortisone to patients with septic shock who are treated with hydrocortisone?
Although previous clinical trials have shown reduced mortality with combined hydrocortisone-fludrocortisone, guidelines recommend...
Mazen Kherallah
Mar 28, 20232 min read
The Wonder Drug Again: Early Hydrocortisone Treatment Saves Lives from Severe Pneumonia!
The potential of glucocorticoids to reduce mortality in patients with severe community-acquired pneumonia through their anti-inflammatory...
Mazen Kherallah
Mar 25, 20234 min read
Turning the Tide: Can Active Fluid De-resuscitation Enhance Outcomes in Septic Shock Patients?
De-resuscitation in septic shock refers to the process of actively removing excess fluids from a patient after their condition is stabalized
Mazen Kherallah
Mar 15, 20233 min read
Colistin: A Useful Past, But Time to Move Beyond
The OVERCOME trial (Colistin Monotherapy Versus Combination Therapy for Carbapenem-Resistant Organisms), published in NEJM Evidence, is...
Mazen Kherallah
Mar 14, 20233 min read
Beta-lactamases and Beta-lactamase Inhibitors: What does the Intensivist Need to Know?
Multidrug-resistant (MDR) organisms have become a major concern in Intensive Care Units (ICUs) worldwide. These organisms are bacteria...
Mazen Kherallah
Mar 12, 20235 min read
Revolutionizing Healthcare: The Promise and Challenges of AI in Medicine
Artificial Intelligence (AI) refers to the use of computer systems to perform tasks that typically require human, such as...
Mazen Kherallah
Feb 5, 20235 min read
CLASSIC vs CLOVERS Trial for Fluid Strategy
The results of the CLOVERS trial are now released at NEJM and revealed that 90-day mortality is not different between conservative fluid...
Mazen Kherallah
Jan 23, 20233 min read
Use of Anesthetic Conserving Devices in ICU Sedation
Critical care is shifting towards using volatile anesthetics such as isoflurane and sevoflurane as sedatives for patients on mechanical...
Mazen Kherallah
Jan 18, 20234 min read
Sedation Algorithm for Intubated Patients
The above algorithm is developed based on the society of critical care medicine PADIS guidelines with overall objectives to: Address pain...
Mazen Kherallah
Dec 6, 20226 min read
COVID-19 Treatment Update
The pathogenesis of COVID-19 is driven by two main processes: replication of SARS-CoV-2 and a dysregulated immune/inflammatory response....
Mazen Kherallah
Nov 12, 20224 min read
Cough Assist in Mechanically Ventilated Patients
Mechanical insufflation-exsufflation is a technique that uses pressure to help clear secretions from the lungs. There is limited evidence on
Mazen Kherallah
Nov 11, 20223 min read
Neurological Prognostication after Cardiac Arrest: What Every Intensivist Should Know!
Determination of poor neurological prognosis after cardiac arrest can be best done at least 72 hours after ROSC
Mazen Kherallah
Nov 5, 20225 min read
The PILOT Trial and Evolution of Evidence for Oxygen Targets in the Critically Ill Patients
It appears that there is no significant difference in mortality or other outcomes when critically ill patients are given a conservative oxyg
Mazen Kherallah
Oct 27, 20225 min read
Selection of Paralytic and Induction Agents in RSI
Selection of a paralytic and induction agents in rapid sequence intubation (RSI).
Mazen Kherallah
Oct 25, 20227 min read
Evolution on Evidence for ECCO2R Use in ARDS Patients
Even though extracorporeal CO2 removal might appear appealing because it helps reduce the mechanical force of ventilation, evidence showed
Mazen Kherallah
Oct 18, 20223 min read
Echocardiographic Signs of Right Ventricular Strain in Acute Pulmonary Embolism
Right ventricular (RV) strain, as seen on echocardiography, is a common finding in patients with pulmonary embolism (PE). This is due to...
Mazen Kherallah
Oct 14, 20225 min read
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