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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Feedback Mechanism in Volume Support Ventilation
Volume support (VS) ventilation is a variable pressure support that targets a preset tidal volume. It is a spontaneously triggered mode wher

Mazen Kherallah
Jan 18, 20223 min read


Patient-Ventilator Interaction & Asynchrony
Patient-ventilator asynchrony (PVA) is a mismatch between the patient's demand and the ventilator during a ventilator breath delivery.

Mazen Kherallah
Jan 14, 20224 min read


Bedside Lung Ultrasound in Emergency: The Blue-Protocol
The BLUE-protocol combines certain ultrasound signs (lung sliding, A lines, B lines, and PLAPS) with location, associated with results of..

Mazen Kherallah
Jan 6, 20222 min read


Lung ultrasound for the diagnosis of pneumonia in adults: Blue Protocol
Ultrasound in the intensive care unit is a reasonable gold standard to detect many causes of respiratory failure with good sensitivity and..

Mazen Kherallah
Jan 5, 20222 min read


Assessment of Hyponatremia: Four Critical Questions!
The diagnosis of hyponatremia in the ICU can be made easy in a systematic way by answering four main questions, read more..

Mazen Kherallah
Jan 1, 20222 min read


Mechanical Power: New Target for VILI Prevention
Ventilator-induced Lung Injury (VILI) is the unwanted result of a complex interplay of multiple factors on mechanical ventilation. These...

Mazen Kherallah
Dec 29, 20215 min read


Mechanical Ventilation in Obese Patients
Selection of plateau pressure and PEEP in obese patients with ARDS and on mechanical ventilation.

Mazen Kherallah
Dec 25, 20213 min read


Protective Lung Strategy Targets in ARDS
Targets of protective lung strategy with emphasis on driving pressure and transpulmonary pressure

Mazen Kherallah
Dec 21, 20213 min read


LIP and UIP may not be adequate to determine PEEP and plateau pressure in ARDS patients!
LIP and UIP May Not be Adequate to Determine PEEP and Plateau Pressure in ARDS Patients

Mazen Kherallah
Dec 19, 20211 min read


A Decision Algorithm in the Management of Pulmonary Embolism
Therapies for acute pulmonary embolism are determined based on the risk of death, risk of bleeding, and response to initial therapy....

Mazen Kherallah
Dec 16, 20212 min read


Omicron "A Variant of Concern"
The CDC defines the "Variant of Concern" (VOC) for an new variant for which there is evidence of an increase in transmissibility, more...

Mazen Kherallah
Dec 6, 20211 min read


Pathophysiology-based Understanding of Respiratory Failure
The respiratory failure is an imbalance between the load (resistive, elastic, or metabolic) and the neuromuscular competence

Mazen Kherallah
Nov 24, 20212 min read


Stepwise Approach in the Management of ARDS*
Various interventions visually and the following text explains the evidence supporting these interventions.

Mazen Kherallah
Nov 20, 20214 min read


Management of Status Epilepticus
A stepwise approach to the management of status epilepticus in adults of more than 40 Kg of weight based on the most recent evidence.

Mazen Kherallah
Nov 11, 20211 min read


Anticoagulation in Continuous Renal Replacement Therapy
Dialysis fiber clotting can be a major issue encountered during prolonged sessions of continuous renal replacement therapy (CRRT) in the...

Mazen Kherallah
Nov 8, 20211 min read


Low vs Higher Dose Dexamethasone for COVID-19 Patients
In this trial, the adjusted point estimate for 28-day mortality was 4.5 percentage points lower in the 12 mg of dexamethasone group than...

Mazen Kherallah
Oct 26, 20211 min read


Clipping or Coiling for Ruptured Cerebral Aneurysms!
The goal of both surgery (clipping) and endovascular (coiling) treatment is to exclude the lumen of the aneurysm from circulation while pres

Mazen Kherallah
Oct 24, 20211 min read


Progression of EEG in Metabolic Encephalopathy
Normal EEG waves: Beta (14-30 Hz), Alpha: 8-13, Theta (4-7 Hz), Delta (<3.5 Hz): The earliest signs of metabolic encephalopathy is a mild...

Mazen Kherallah
Sep 19, 20211 min read


Anticoagulation in COVID-19
It seems that selected group of patients may benefit of full anticoagulation but has to start early enough before organ damage occurs.

Mazen Kherallah
Sep 3, 20213 min read


Decompressive Craniectomy and a Stepwise Approach to Elevated ICP in Patients with Severe TBI
Elevated intracranial pressure (ICP) is associated with increased mortality and worse outcome in patients with traumatic brain injury...

Mazen Kherallah
Aug 28, 20212 min read
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