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Respiratory Failure & Mechanical Ventilation

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โ€Žโ€Age/gender : 54y/o male

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๐Ÿ“ โ€Žโ€ Diagnosed as ARDS, H1N1 positive, later found to have ICH

โ€Žโ€ ๐Ÿ—‚๏ธ Medical history : Nil

๐Ÿ‹๐Ÿปโ€โ™‚๏ธ โ€Žโ€Adm wt.60kg, ht.168cm.

โ€Žโ€ Current wt: 54.0

โ€Žโ€๐Ÿ’‰Infusions:

โ€Žโ€๐Ÿ”นFentanyl 100 mcg/hr

๐Ÿ”นMedazolam 5 mg/h

๐Ÿ”น Rocuronium 10 mcg/kg/min (held off)

โ€Žโ€๐Ÿ”นD5N@50ml/hr

โ€Žโ€๐Ÿฉธ RBS: 198mg/dl (RI- LDSS)

โ€Žโ€

โ€Žโ€๐ŸŽ›๏ธECMO V-V : ( Day 4)

โ€Žโ€*FLOW - 4.0

*FIO2 - 50%

*SWEEP - 4

โ€Žโ€*โˆ†p 60

โ€Žโ€

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๐Ÿ”นPatient tachycardia 125-130

๐Ÿ”น Tachypneic in ventilator


Screenshot of the ventilator today is showing the following:

What would you do next:


What changes would you make?

  • 0%Decrease inspiratory time

  • 0%Increase inspiratory time

  • 0%Resume paralytic agent

  • 0%Increase PC level

Thank you Dr. @Ibrahim Ameen for a nice case.

Mazen Kherallah
Mazen Kherallah
Feb 05, 2024

Interesting answers, it looks like this is a case of delayed cycling indicated by increase inspiratory flow at end of inspiration in every single breath. Notice the increase in volume at the same time. This may lead to double triggering if the inspiratory negative pressure continued and was at the level to trigger another breath. However, we need to rule out reverse triggering by applying expiratory hold and notice if these efforts disappear. If they disappear then the answer to the question would be resuming paralysis, if they did not then we need to shorten inspiratory time on the ventilator first and re-evaluate.

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