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INSIGHTS
The critical care medicine blog serves as a specialized platform committed to delivering profound insights and current knowledge on the cutting-edge advancements within critical care. With its broad coverage of meticulously examined critical care topics, the blog furnishes evidence-based responses to critical care questions, offering a comprehensive understanding of the subject matter. Stay informed with in-depth analysis and up-to-date information through our blog!
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Ventricular-Arterial Coupling (Ea/Ees Ratio)
Ventricular-arterial coupling is a dynamic interplay between ventricular contractility and arterial load.

Mazen Kherallah
Jun 29, 20242 min read


Does Achieving Better β-lactam Pharmacokinetic Targets Translate to Better Clinical Outcomes in Septic Patients?
Continuous infusion of β-lactam antibiotics holds promise for better outcomes in sepsis treatment.

Mazen Kherallah
Jun 19, 20243 min read


Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation
PPIs can reduce gastrointestinal bleeding and possibly mortality in less severely ill patients, they do not significantly impact mortality.

Mazen Kherallah
Jun 16, 20242 min read


Post-Spontaneous Breathing Trial Reconnection to Mechanical Ventilation for Alveolar Recruitment Recovery
These findings highlight the importance of post-SBT reconnection in recovering alveolar derecruitment after SBT.

Mazen Kherallah
Jun 9, 20242 min read


Understanding Preload of the Left Ventricle: A Key Concept in Cardiovascular Physiology
Preload is a fundamental concept in cardiovascular physiology, essential for understanding the mechanics of the heart. It refers to the...

Mazen Kherallah
May 29, 20243 min read


Hemodynamic Profile in Sepsis and Septic Shock Associated with Vasoplegia: A Pressure-Volume Diagram Perspective
Sepsis is a life-threatening condition characterized by an overwhelming immune response to infection, leading to widespread inflammation...

Mazen Kherallah
May 26, 20243 min read


AI in Critical Care Medicine
AI's integration into critical care medicine offers substantial benefits but also presents challenges that need to be addressed.

Mazen Kherallah
May 22, 20243 min read


Ventricular Pressure-volume Loop in Normal Heart
The pressure-volume loop and its parameters (EDVPR, ESVPR, Ea, Ea/Ees) assess heart function, aiding decisions and improving outcomes

Mazen Kherallah
May 19, 20248 min read


Advanced CT Perfusion Imaging in Stroke Management: A Detailed Insight
CT perfusion imaging enhances stroke diagnosis and treatment, improving outcomes by identifying specific brain perfusion patterns.

Mazen Kherallah
May 7, 20243 min read


The Silent Sacrifices of the Intensivist!
This narrative highlights the unspoken hardships and dedication of healthcare workers, who serve not for glory but to make a difference.

Mazen Kherallah
Apr 13, 20243 min read


What is the Evidence for Contrast-induced Nephropathy (CIN)?
Recent research shows minimal CIN risk from CT contrast, with strategies in place for prevention and ensuring safety.

Mazen Kherallah
Apr 11, 20244 min read


The Critical Need for Standardizing Norepinephrine Formulation Reporting in Intensive Care
This study underscores the need for standardized norepinephrine reporting to improve care and research in critical care medicine globally.

Mazen Kherallah
Mar 17, 20243 min read


Etomidate versus Ketamine for RSI
Recent findings suggest ketamine may lower mortality compared to etomidate, but study limitations remain.

Mazen Kherallah
Mar 11, 20242 min read


What is Reverse Triggering?
Reverse triggering in ventilation is reflexive patient breathing due to ventilator stimuli, requiring careful management to avoid lung stre

Mazen Kherallah
Jan 27, 20243 min read


The Impact of Balanced Crystalloids vs. Saline in ICU Patients: A New Meta-Analysis
Balanced crystalloids vs. saline in ICU show 89.5% benefit probability but debate continues.

Mazen Kherallah
Jan 24, 20243 min read


Unveiling the Impact of Corticosteroids in Community-Acquired Pneumonia: A Comprehensive Meta-Analysis
Meta-analysis reveals corticosteroids reduce CAP mortality, especially in severe cases, highlighting tailored therapy benefits

Mazen Kherallah
Jan 22, 20243 min read


Contemplating Lytic Therapy in a Complex Case of Respiratory Decompensation!
Massive pulmonary embolism

Mazen Kherallah
Jan 3, 20242 min read


Hypothermia vs Normothermia in Patients With Cardiac Arrest and Nonshockable Rhythm
Evidence supports using normothermia in patients with coma after cardiac arrest with nonshockable rhythm compared to hypothermia.

Mazen Kherallah
Dec 28, 20235 min read


Cefepime or Piperacillin/tazobactam Empirically for Gram-negative Infections in the Hospital settings
This trial suggests comparable risks of acute kidney injury and death between cefepime and piperacillin/tazobactam.

Mazen Kherallah
Dec 23, 20233 min read


Doing Less is Actually Doing More: The NICO Trial!
In cases of coma due to acute poisoning, a conservative airway management strategy could be more beneficial than routine intubation.

Mazen Kherallah
Dec 6, 20232 min read
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